Calprotectin

Calprotectin (MRP8, S100A8/MRP8/14, S100A9) also known as fCAL, is a protein found extensively in the cytoplasm of neutrophils. It has been shown to be extremely useful in the study and monitoring of inflammatory diseases in the gastrointestinal tract.

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Assays

The BÜHLMANN Calprotectin Assay product line has a range solutions that services all types of users, from the subject’s home test to the high throughput labs running thousands of samples.

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Technical news

(by Dr. Christian Reinhard)
The Value of Calprotectin in Inflammatory Bowel Disease (IBD) Monitoring. Learn about calprotectin and its value in IBD patient monitoring, and treatment pathways.

Closer Look

Gastroenterology Research is our Focus, Quality is our Standard, and Flexible Innovative Solutions are our Mission. Take a closer look and learn full circle about IBD here with BUHLMANN.

Calprotectin

Calprotectin (MRP8, S100A8/MRP8/14, S100A9) also known as fCAL, is a protein found extensively in the cytoplasm of neutrophils. It has been shown to be extremely useful in the diagnosis and monitoring of inflammatory diseases in the gastrointestinal tract.

Key Facts of fecal calprotectin:

  • Calcium- and zinc-binding molecule, which plays a role in anti-microbial activity
  • Heterodimer consisting of the (MRP8, S100A8) and (MRP8/14, S100A9) subunits
  • Highly abundant in neutrophils
  • Highly useful marker for studying intestinal inflammation

Citations

Access valuable resources and view our complete list of peer review publications that cite and support our calprotectin assays.

Literature

View a full array of informational product flyers and learn more about the technical details of BÜHLMANN Calprotectin solutions.

Videos

Watch BÜHLMANN videos to get an up close look at our calprotectin assays. Learn about their applications, workflow, related research, and more.

The Value of Calprotectin

In Inflammatory Bowel Disease Monitoring

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About BUHLMANN

BÜHLMANN has developed into THE CALPROTECTIN COMPANY with highest quality standards and its determination to increase the knowledge and application of fecal calprotectin (fCAL). BÜHLMANN offers the broadest calprotectin product range in the industry including BÜHLMANN fCAL® ELISA, BÜHLMANN fCAL® turbo for testing on most clinical chemistry analyzers, quantitative Quantum Blue® Calprotectin rapid tests, and IBDoc® smartphone for at home testing (IBDoc Not for Sale in US or Canada). All calprotectin products benefit from our patented easy, safe, and clean stool CALEX® sampling and extraction devices.

The BÜHLMANN calprotectin Assay range has solutions that services all types of users:

  • Quantum Blue® Rapid Assays for Point of Care and low throughput use.
  • fCal ELISA for higher throughput laboratory use with automation available on the Dynex DS2™ ELISA Processing System.
  • IBD home monitoring with the IBDoc system (Not Available for sale in US or Canada).

EUROPE

per 100,000 persons, Ulcerative Colitis (UC)

per 100,000 persons, Crohn’s Disease (CD)

NORTH AMERICA

per 100,000 persons, Ulcerative Colitis (UC)

per 100,000 persons, Crohn’s Disease (CD)

SOURCES AND REFERENCES

Molodecky, N. A. et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 142, 46–54.e42; quiz e30 (2012). http://dx.doi.org/10.1053/j.gastro.2011.10.001

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